The win is the Lancers' fourth straight as they improve to 9-1-1 overall, 5-0-1 PacWest, winning the first of four games in eight days. Their unbeaten streak has now reached nine games.
The Silverswords fall to 1-12, 1-7.
CBU scored two goals in each half, and Nicassio bookended them, starting things off in the 23rd minute and then completing the Lancers' scoring in the 72nd minute. She now leads the team with 10 goals and has moved into third place on the Lancers' career scoring list with 44 career strikes, just four away from tying Courtney Firth's program record of 48.
She also has 103 career points, becoming just the fourth player in program history to surpass the 100-point plateau.
The Lancers outshot Chaminade, 20-6, including a 10-0 advantage in the first half when they took the lead. Eleven of the Lancers' shots were on frame.
After Nicassio gave the Lancers an early lead, da Silva doubled the advantage with her fifth goal of the season in the 41st minute. She then assisted on the Lancers' final two strikes.
Lindsay Vesling gave the Lancers a 3-0 lead in the 66th minute when she took a through ball from da Silva and easily beat Chaminade keeper Kainoa Makua.